The Effect of Moringa Leaf Administration on Hb Levels in 3rd Semester Pregnant Women
DOI:
https://doi.org/10.57214/jasira.v4i1.319Keywords:
Hemoglobin, Moringa Leaves, Pregnancy Anemia, Pregnant Women, Second TrimesterAbstract
Anemia during pregnancy is a major public health issue, especially in developing countries like Indonesia, contributing to maternal morbidity and adverse pregnancy outcomes. The second trimester, marked by increased iron needs due to plasma volume expansion and fetal growth, is critical for preventing anemia. Moringa leaves (Moringa oleifera), rich in micronutrients, may serve as an effective nutritional intervention to enhance hemoglobin levels in pregnant women. This study aimed to assess the impact of moringa leaf supplementation on hemoglobin levels in second-trimester pregnant women. Using a one-group pretest-posttest quasi-experimental design, the study was conducted at the Tadoy Community Health Center in Bolaang Mongondow Regency from October to November 2025, involving 25 pregnant women selected via purposive sampling. Hemoglobin levels were measured before and after the supplementation. Data analysis, including the Shapiro-Wilk test and Wilcoxon Signed Rank Test, indicated significant changes in hemoglobin levels (p = 0.000). The results showed a notable increase in hemoglobin levels post-supplementation, supporting the potential of moringa leaves as a safe, affordable, and effective intervention. This finding suggests that moringa leaves could be integrated into antenatal care and nutrition education to help prevent anemia in pregnant women.
References
Achebe, M. M., & Gafter-Gvili, A. (2017). How I treat anemia in pregnancy: Iron, cobalamin, and folate. Blood, 129(8), 940-949. https://doi.org/10.1182/blood-2016-08-672246
Bencaiova, G., Burkhardt, T., & Breymann, C. (2012). Anemia-prevalence and risk factors in pregnancy. European Journal of Internal Medicine, 23(6), 529-533. https://doi.org/10.1016/j.ejim.2012.04.008
Boateng, L., Nortey, T. N. N., & Obeng-Baah, J. (2019). The effect of Moringa oleifera supplementation on hemoglobin levels in pregnant women. African Journal of Reproductive Health, 23(4), 38-46.
Bothwell, T. H. (2017). Iron requirements in pregnancy and strategies to meet them. American Journal of Clinical Nutrition, 106(6), 1564S-1571S. https://doi.org/10.3945/ajcn.117.155135
Chaparro, C. M., & Suchdev, P. S. (2019). Anemia epidemiology, pathophysiology, and etiology in low- and middle-income countries. Annals of the New York Academy of Sciences, 1450(1), 15-31. https://doi.org/10.1111/nyas.14092
Daru, J., Zamora, J., Fernández-Félix, B. M., Vogel, J., Oladapo, O. T., Morisaki, N., … Khan, K. S. (2018). Risk of maternal mortality in women with severe anemia during pregnancy and postpartum: A multilevel analysis. The Lancet Global Health, 6(5), e548-e554. https://doi.org/10.1016/S2214-109X(18)30078-0
Dhakar, R. C., Pooniya, B. K., Gupta, M., Maurya, S. D., & Bairwa, N. (2019). Moringa: The herbal gold to combat malnutrition. Chronicles of Young Scientists, 2(3), 119-125. https://doi.org/10.4103/2229-5186.90887
FIGO. (2019). FIGO statement on iron deficiency and anemia in women and girls. International Federation of Gynecology and Obstetrics.
Gera, T., Sachdev, H. S., & Nestel, P. (2016). Effect of iron supplementation on hemoglobin response. Public Health Nutrition, 19(2), 204-214.
Gopalakrishnan, L., Doriya, K., & Kumar, D. S. (2016). Moringa oleifera: A review on nutritive importance and its medicinal application. Food Science and Human Wellness, 5(2), 49-56. https://doi.org/10.1016/j.fshw.2016.04.001
Hurrell, R., & Egli, I. (2019). Iron bioavailability and dietary reference values. American Journal of Clinical Nutrition, 91(5), 1461S-1467S. https://doi.org/10.3945/ajcn.2010.28674F
Iskandar, I., Hadju, V., & Indriasari, R. (2021). Effect of Moringa oleifera supplementation on hemoglobin levels among pregnant women. Journal of Nutrition and Metabolism, 2021, 1-7. https://doi.org/10.1155/2021/5590123
Kushwaha, S., Chawla, P., & Kochhar, A. (2018). Effect of supplementation of drumstick (Moringa oleifera) leaves on hemoglobin level. International Journal of Food and Nutritional Sciences, 7(3), 1-6.
Leone, A., Spada, A., Battezzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2018). Cultivation, genetic, ethnopharmacology, phytochemistry and pharmacology of Moringa oleifera leaves: An overview. International Journal of Molecular Sciences, 16(6), 12791-12835. https://doi.org/10.3390/ijms160612791
López, A., Cacoub, P., Macdougall, I. C., & Peyrin-Biroulet, L. (2016). Iron deficiency anemia. The Lancet, 387(10021), 907-916. https://doi.org/10.1016/S0140-6736(15)60865-0
Milman, N. (2015). Iron deficiency and anemia in pregnant women. Acta Haematologica, 133(2), 124-133.
Milman, N., Taylor, C. L., Merkel, J., & Brannon, P. M. (2017). Iron status in pregnant women. American Journal of Clinical Nutrition, 106(6), 1655S-1662S. https://doi.org/10.3945/ajcn.117.156000
Ministry of Health of the Republic of Indonesia. (2018). 2018 National Riskesdas Report. Jakarta: Health Research and Development Agency.
Ministry of Health of the Republic of Indonesia. (2020). Guidelines for the prevention and control of anemia in pregnant women. Jakarta: Ministry of Health of the Republic of Indonesia.
Nambiar, V. S., & Daniel, M. (2019). Moringa oleifera leaves in anemia management. Journal of Herbal Medicine, 17, 18, 100256.
Nambiar, V. S., Mehta, R., & Daniel, M. (2017). Polyphenol content of drumstick leaves (Moringa oleifera) and their role in anemia management. Journal of Food Science and Nutrition, 3(2), 55-61.
Oppenheimer, S. J. (2016). Iron and its relation to immunity and infectious disease. Journal of Nutrition, 131(2), 616S-635S. https://doi.org/10.1093/jn/131.2.616S
Pasricha, S. R., Tye-Din, J., Muckenthaler, M. U., & Swinkels, D. W. (2021). Iron deficiency. The Lancet, 397(10270), 233-248. https://doi.org/10.1016/S0140-6736(20)32594-0
Permatasari, T. A. E., Rizqiya, F., Kusumaningati, W., Suryaalamsah, I. I., & Hermiwahyoeni, Z. (2021). Determinants of anemia among pregnant women in Indonesia: A population-based study. BMC Pregnancy and Childbirth, 21(1), 1-10. https://doi.org/10.1186/s12884-021-03644-2
Rahman, M. M., Rahman, M. M., & Rahman, S. M. (2021). Bioavailability of iron from Moringa oleifera leaves and its potential role in anemia prevention. Nutrients, 13(7), 2291. https://doi.org/10.3390/nu13072291
Stevens, G. A., Paciorek, C. J., Flores-Urrutia, M. C., Borghi, E., Namaste, S., Wirth, J. P., … Ezzati, M. (2022). National, regional, and global estimates of anaemia by severity in women of reproductive age. The Lancet Global Health, 10(5), e627-e639. https://doi.org/10.1016/S2214-109X(22)00084-5
Stoltzfus, R. J. (2017). Iron deficiency: Global prevalence and consequences. Food and Nutrition Bulletin, 38(2), 165-172.
World Health Organization. (2016). WHO recommendations on antenatal care for a positive pregnancy experience. Geneva: WHO.
World Health Organization. (2017). Nutritional anaemias: Tools for effective prevention and control. Geneva: WHO.
World Health Organization. (2019). Anaemia in women and children. Geneva: WHO.
World Health Organization. (2023). Global anaemia estimates 2023. Geneva: WHO.
Zimmermann, M. B., & Hurrell, R. F. (2007). Nutritional iron deficiency. The Lancet, 370(9586), 511-520. https://doi.org/10.1016/S0140-6736(07)61235-5
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